Once part of a much larger Haut Medoc estate, Château Chasse-Spleen has a rich and unique history. Established in In 182, there are many rumours trying to explain the name of Chateau Chasse-Spleen. One is that in 1821 Lord Byron visited the estate and proclaimed "Quel remede pour chasser le spleen", which when loosely translated means, What remedy to remove the spleen?
Changing several hands between first world war and 1976, Château Chasse-Spleen was bought by the Merlaut family, eventual owners of various Bordeaux wine Chateaux including Gruaud Larose, Ferriere, Citran and Haut-Bages-Liberal.
Tragedy struck in 1992 when Jacques Merlaut's daughter Bernadette Villars and her husband died in a mountaineering accident. Château Chasse-Spleen is now run by her daughter Claire Villars.